C. Dewey Buescher
PhD Candidate (curriculum vitae)
Towards the fundamental understanding of hemodynamics in vein and venous valve system: an experimental study.
Year Started:  Spring 2003
Anticipated Graduation:  Spring 2007
Advisor:  Dr. Karlene A. Hoo

B.S. Chemical Engineering, Texas tech University, Lubbock, TX, May, 2000.

A major goal of this project is to develop an improved phenomenological understanding of the basics of hemodynamics in the vein and venous valves through computer aided visualization and measurements of pressure and mass flowrate through the the venous valve. Experiments will be conducted in vitro (harvested veins) and in situ using both fiber optic techniques, external visualization and LabView® data acquisition techniques. Ultimately, we hope to develop a mechanical model based on the measurements and theoretical understanding of the hemodynamic mechanisms of the venous system so that flow patterns can be predicted with a known degree of certainty at a wide range of conditions. After this is completed, we will be able to use this model to understand the associations between venous/valve function and basic systemic biological activities, such as blood circulation, under different physiologic transport conditions that may lead to chronic venous insufficiency and deep venous thrombosis.
Progress to Date:  Also See http://www.che.ttu.edu/faculty/hoo2/bioResearch.htm
  1. Refereed manuscripts: For reprints contact K. A. Hoo (khoo@coe.ttu.edu)
    Buescher, C. D., Z. I. Stefanov, K. A. Hoo and H. F. Jansen, "Stereo-Imaging of Collapsible Tubes with Embedded One-way Bicuspid Membrane Structures" Submitted to Biomedical Imaging, 2004.
    Buescher, C. D., B. Nachiappan, J. Brumbaugh, K. A. Hoo, and H. F Jansen, "Experimental Studies of the Effects of Abnormal Bicuspid Valves on Fluid Flow"  Biotechnology Progress, Vol. 21, No. , pp 938-945, 2005.
  2. Invited Conference: 2004 AIChE national meeting, Austin, TX, "Experimental Evaluation of the Physiologic Response of the Venous Valve".