B.S. in Chemical Engineering, University College of Technology, Osmania University (OUCT), India (2003).
M.S. in Chemical Engineering, Department of Chemical Engineering, Auburn University, AL (2006).
M.S. Thesis: "Characterization and Kinetic Investigation of Cellulase Enzymes Using
Non-Crystalline Cellulose and Cello-Oligosaccharides."
Ph.D. Chemical Engineering, Texas Tech University,
Phone: (806)-742-5073 ext 249
Fax: (806) 742-3552
PhD Research Topic:
Computational Studies of Cellulose Degradation for the Production of Biofuels
The main aim of my research is to quantitatively study the non-reaction factors associated with the hydrolysis of cellulose using molecular simulations. Specifically, this work focuses on developing a fundamental understanding of the interactions of cello-oligosaccharides with cellulose crystal surface and water using molecular dynamics simulations. We perform umbrella sampling simulations to calculate the free energies involved in the separation of cello-oligosaccharides from each other and also from the cellulose crystal surface. Simulation studies are validated against the experimental results obtained by collaborators at Texas Tech University.
- Peri, S.; Karim, M. N.; Khare R.; “Potential of Mean Force for Separation of the Repeating Units in Cellulose and Hemicellulose”, submitted.
- Suma Peri, Srinivas Karra, Y.Y. Lee, and M. Nazmul Karim, 2007, “Modeling Intrinsic Kinetics of Enzymatic Cellulose Hydrolysis”, Biotechnology Progress, 23(3), 626-637.
- Suma Peri, Srinivas Karra, Y.Y. Lee, and M. Nazmul Karim, 2007, “Modeling for Optimization of Enzymatic Hydrolysis of Cellulose”, in 10th International IFAC Symposium on Computer Applications in Biotechnology, Conference Proceedings, pp: 129-134, 2007.
- Suma Peri*, Nazmul M. Karim, and Rajesh Khare, “Calculation of Free Energy Involved in Saccharification of Cellulose using Molecular Dynamics Simulations”, in Thermodynamics of Polymers, The 2009 Annual Meeting, Nov 7-13, 2009, Nashville, TN.
- Suma Peri*, Nazmul M. Karim, and Rajesh Khare, “Mechanism of Cellulose degradation – Free energy calculations for separation of cellulose chains using molecular modeling techniques”, in Bio-process Molecular Modeling of Biophysical Processes I, The 2007 Annual Meeting, Nov 4-9, 2007, Salt Lake City, UT.
- Srinivas Karra, Suma Peri, Rajesh Khare and Nazmul M. Karim*, “Problems and Opportunities in Starch and Lignocellulose-based Ethanol Production”, in Biochemical Engineering XV: Engineering Biology from Biomolecules to complex systems, July 15-19, 2007, Quebec City, Canada.
- Suma Peri, Srinivas Karra, Y.Y. Lee, and Nazmul M. Karim*, “Modeling for Optimization of Enzymatic Hydrolysis of Cellulose", in 10th International IFAC Symposium on Computer Applications in Biotechnology, June 4-6, 2007, Cancun, Mexico.
- Suma Peri, Nazmul M. Karim and Rajesh Khare*, “Molecular Modeling Investigation of Non-reaction Factors in the Enzymatic Hydrolysis of Cellulose”, 29th Symposium on Biotechnology for Fuels and Chemicals, April 29 – May 2, 2007, Denver, CO.
- Suma Peri*, Srinivas Karra and Nazmul M. Karim, “A Comprehensive Kinetic Investigation of Enzymatic Hydrolysis of Cellulose”, in Bio-process Modeling and Control, The 2006 Annual Meeting, Nov 12-17, 2006, San Francisco, CA.
- Suma Peri*, Nazmul M. Karim and Rajesh Khare, “Free Energy of Separation of Glucose Oligomers in Water”, 30th Symposium on Biotechnology for Fuels and Chemicals, May 4 – 7, 2008, New Orleans, LA.
- Suma Peri*, Nazmul M. Karim and Rajesh Khare, “Non-reaction Factors in the Enzymatic Hydrolysis of Cellulose to Ethanol: A Molecular Simulation Study”, 7th Annual Graduate Student Research Poster Competition, March, 2008, TTU, Lubbock, TX.
Honors and Awards:
- Third Prize winner in the Seventh Annual Graduate Student Research Poster Competition, March, Texas Tech University, Lubbock, TX (2008).
- Chancellor’s fellowship recipient for the years of 2006-2009, TTU.
Dynamics of cello-oligosaccharide on cellulose crystal surface
For further assistance in these areas, contact Dr. Rajesh Khare.
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